Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep811 | Obesity | ECE2016

Positive association between blood natural killer T cells and liver enzymes ALT, AST and GGT levels

Lopez Soledad , Pozo David , Garcia-Serrano Sara , Gutierrez-Repiso Carolina , Rodriguez-Pacheco Francisca , Ho-Plagaro Ailec , Alaminos-Castillo Miguel A , Valdes Sergio , Gonzalo Montserrat , Andrade Raul J. , Garcia-Fuentes Eduardo

Introduction: Obesity is associated to a pro-inflammatory state with a different pattern of response from the classical response. Also, obesity is associated to non-alcoholic fatty liver disease (NAFLD). In this sense, natural killer T (NKT) cells are a subset of innate immune cells that abundantly reside within the liver and are readily activated by lipid antigens. However, the phenotype and functional characteristics of these cells are no clear in the immune homeostasis in o...